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Mean reduction (mm Hg) in sitting diastolic blood pressure (msDBP) in hypertensive patients treated with sacubitril/valsartan compared to ARB-treated controls. (a) In the control group olmesartan was used as comparator. (b) In the control group valsartan was used as comparator. pts: patients; st.dev: standard deviation; ctrl: controls; ARBs: angiotensin receptor blockers; CI: confidence interval.
