Kundu 2007.

Methods	Parallel RCT Ethics committee: approved by institutional ethics committee Informed consents: informed written consents were taken from all participants Site: National Institute of Cardiovascular Diseases (NICVD), Dhaka, Bangladesh Setting: university hospital Dates of data collection: between July 2006 and March 2007 Funding: unspecified Registration: unspecified
Participants	40 participants: mean age: 51.2; sex distribution: 6 females and 34 males Inclusion criteria ASA II or III patients Aged between 40 and 65 years LVEF ≥ 40% Scheduled for off‐pump CABG Exclusion criteria Left main artery coronary disease Any contraindication to neuraxial block or catheter placement Hypersensitivity to any drugs used in the study Taking antiplatelet and anticoagulant drugs within 3 to 5 days before operation
Interventions	Intervention Epidural analgesia (N = 20) Comparator Systemic analgesia (N= 20) Premedication: diazepam Induction: midazolam, morphine, and pancuronium bromide Maintenance: halothane, midazolam, morphine, and pancuronium bromide Surgery: off‐pump CABG
Outcomes	Relevant to this review Risk of myocardial infarction Risk of atrial fibrillation or atrial flutter Haemodynamic variables Other Myocardial ischaemia
Notes	Correspondence: letter sent 16 March 2018; no reply Conflict of interest: not reported DOI: n/a
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Quote: "randomly selected and divided in two groups"
Allocation concealment (selection bias)	Unclear risk	Not reported
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Not reported
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Not reported
Incomplete outcome data (attrition bias) All outcomes	Low risk	All results reported
Selective reporting (reporting bias)	Low risk	No loss to follow‐up
Other bias	Low risk	No failed epidural mentioned Groups well balanced