Stenseth 1994.

Methods	Parallel RCT Ethics committee: approved by the Ethics Committee of the University of Trondheim Informed consents: obtained Site: Trondheim, Norway Setting: university hospital Dates of data collection: unspecified Funding: departmental/institutional Registration: unspecified
Participants	28 participants: mean age: 54.9 years; sex distribution: 28 males Inclusion criteria Male ASA III patients < 65 years LVEF > 50% Undergoing CABG for double‐vessel or triple‐vessel disease Exclusion criteria Not reported
Interventions	Intevention Epidural analgesia and high‐ (N = 10) or low‐dose fentanyl (N = 8) Comparator Systemic analgesia (N = 10) Premedication: morphine and scopolamine Induction: thiopentone and pancuronium Maintenance: fentanyl, diazepam, and nitrous oxide Surgery: CABG with CPB
Outcomes	Relevant to this review Risk of mortality Risk of myocardial infarction Haemodynamic variables Others Use of vasoactive drugs
Notes	Correspondence: data no longer available Conflict of interest: none reported DOI: n/a
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Quote: "randomized"; no details
Allocation concealment (selection bias)	Unclear risk	Not reported
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Not reported
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Not reported
Incomplete outcome data (attrition bias) All outcomes	Low risk	Two participants were excluded from the final analysis due to surgical problems
Selective reporting (reporting bias)	Low risk	All results reported
Other bias	Unclear risk	Not in intention‐to‐treat Groups had similar demographic data