Yilmaz 2007.

Methods	Parallel RCT Ethics committee: approved by the ethics committee Informed consents: not reported Site: Yeditepe University Hospital, Department of Anesthesiology and Reanimation Anabilim; Psychiatry Ersek Chest Cardiovascular Center; Anesthesia Clinic and Special Swiss Hospital Breast Cardiovascular Anesthesiology, Turkey Setting: university hospital Dates of data collection: not reported Funding: unspecified Registration: unspecified
Participants	34 participants; mean age: 55.7 years; sex distribution: 7 females and 27 males Inclusion criteria ASA II to III Aged < 70 years LVEF > 40% Undergoing elective CABG Exclusion criteria Not reported
Interventions	Intervention Epidural analgesia (N = 17) Comparator Systemic analgesia (N = 17) Premedication: atropine and midazolam Induction: fentanyl, midazolam, and pancuronium Maintenance: fentanyl, midazolam, and isoflurane Surgery: CABG with CPB
Outcomes	Relevant to this review Risk of pulmonary complications (pneumonia) Time to tracheal extubation Risk of neurological complications (serious neurological complications from epidural analgesia) Pain scores Haemodynamic variables Others Rescue analgesia Lung function tests
Notes	Correspondence: letter sent 16 March 2018; no reply Conflict of interest: not reported DOI: n/a
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Quote: "randomized"; no details provided
Allocation concealment (selection bias)	Unclear risk	Quote: "randomized"; no details provided
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Not reported
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Not reported
Incomplete outcome data (attrition bias) All outcomes	Low risk	No loss to follow‐up
Selective reporting (reporting bias)	Low risk	All results reported
Other bias	Low risk	No failed epidural mentioned Groups well balanced