Yung 1997.

Methods	Parallel RCT Ethics committee: not reported Informed consents: obtained Site: Veterans General Hospital‐Taipei and National Yang‐Ming University School of Medicine, Taipei, Taiwan, ROC Setting: university hospital Dates of data collection: from June 1995 to December 1995 Funding: unspecified Registration: unspecified
Participants	40 participants; mean age: 66.6 years; sex distribution: 5 females and 35 males Inclusion criteria Scheduled for CABG Exclusion criteria LVEF < 30% Previously prescribed digitalis and beta‐blocker medications
Interventions	Intervention Epidural analgesia (N = 20) Comparator Systemic analgesia (N = 20) Induction and maintenance: etomidate, vecuronium, fentanyl, and isoflurane Surgery: CABG with CPB
Outcomes	Relevant to this review Risk of pulmonary complications (respiratory depression) Risk of neurological complications (risk of serious neurological complications from epidural analgesia) Tracheal extubation Pain scores Others Rescue analgesia
Notes	Correspondence: letter sent 16 March 2018; no reply Conflict of interest: not reported DOI: n/a
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Quote: "randomly selected and randomly divided into two groups"; no details provided
Allocation concealment (selection bias)	Unclear risk	Not reported
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Not reported
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Not reported
Incomplete outcome data (attrition bias) All outcomes	Low risk	No loss to follow‐up
Selective reporting (reporting bias)	Low risk	All results reported
Other bias	Low risk	No failed epidural reported Groups well balanced