NCT03719248.
Trial name or title | Thoracic epidural reduces risks of increased left ventricular mass index during coronary artery bypass graft surgery |
Methods | Open‐label, parallel, randomized controlled trial |
Participants | 80 ASA II to IV adults (65 to 75 years old) Inclusion criteria: aortic valve replacement with or without coronary artery bypass grafting Exclusion criteria: ejection fraction 0.3, myocardial infarction within the last 4 weeks, diabetes, severe pulmonary or arterial hypertension, a contraindication for epidural analgesia, administration of ticlopidine within 15 days before surgery and administration of platelet glycoprotein IIb/IIIa inhibitor, significant aortic insufficiency, emergency surgery, poor acoustic windows for adequate echocardiographic assessment, and/or did not undergo an echocardiogram before the operation |
Interventions | Intervention: thoracic epidural Comparator: unspecified |
Outcomes | 1. Cardiac function 2. Other haemodynamic variables 3. Myocardial ischaemia |
Starting date | Started: 1 January 2017 Registered: 15 October 2018 Completed |
Contact information | Not available |
Notes | Found 6 February 2019 |
ASA: American Society of Anesthesiologists physical status.