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. 2019 Mar 1;2019(3):CD006715. doi: 10.1002/14651858.CD006715.pub3

NCT03719248.

Trial name or title Thoracic epidural reduces risks of increased left ventricular mass index during coronary artery bypass graft surgery
Methods Open‐label, parallel, randomized controlled trial
Participants 80 ASA II to IV adults (65 to 75 years old)
Inclusion criteria: aortic valve replacement with or without coronary artery bypass grafting
Exclusion criteria: ejection fraction 0.3, myocardial infarction within the last 4 weeks, diabetes, severe pulmonary or arterial hypertension, a contraindication for epidural analgesia, administration of ticlopidine within 15 days before surgery and administration of platelet glycoprotein IIb/IIIa inhibitor, significant aortic insufficiency, emergency surgery, poor acoustic windows for adequate echocardiographic assessment, and/or did not undergo an echocardiogram before the operation
Interventions Intervention: thoracic epidural
Comparator: unspecified
Outcomes 1. Cardiac function
2. Other haemodynamic variables
3. Myocardial ischaemia
Starting date Started: 1 January 2017
Registered: 15 October 2018
Completed
Contact information Not available
Notes Found 6 February 2019

ASA: American Society of Anesthesiologists physical status.