Table S3.
Protein description | PA + AgNPsa | PAb | PA + AgNPs/PA ratio | P-value |
---|---|---|---|---|
Acetyl-coenzyme A carboxylase carboxyl transferase | 0.853±0.007 | 1.133±0.028 | 0.753 | 4.4416E–5 |
subunit alpha | ||||
Enoyl-[acyl-carrier-protein] reductase (NADH) | 0.742±0.028 | 1.253±0.009 | 0.592 | 2.001E–5 |
3-Oxoacyl-[acyl-carrier-protein] reductase | 0.848±0.006 | 1.160±0.024 | 0.731 | 1.73857E–5 |
3-Oxoacyl-[acyl-carrier-protein] synthase 2 | 0.846±0.008 | 1.152±0.006 | 0.734 | 4.453E–7 |
3-Hydroxydecanoyl-[acyl-carrier-protein] dehydratase | 0.857±0.031 | 1.126±0.032 | 0.761 | 0.00052071 |
Malonyl CoA-acyl carrier protein transacylase | 0.785±0.012 | 1.224±0.048 | 0.641 | 5.6695E–5 |
Beta-ketoacyl-[acyl-carrier-protein] synthase | 0.850±0.026 | 1.141±0.025 | 0.745 | 0.000175211 |
Acetyl-CoA acetyltransferase | 1.135±0.007 | 0.871±0.003 | 1.303 | 1.3897E–7 |
Probable acyl-CoA thiolase | 1.135±0.015 | 0.867±0.008 | 1.309 | 4.5E–6 |
Ribonucleoside-diphosphate reductase | 0.797±0.013 | 1.199±0.028 | 0.665 | 1.84241E–5 |
Polyribonucleotide nucleotidyltransferase | 0.839±0.015 | 1.161±0.019 | 0.722 | 2.0224E–5 |
Adenylosuccinate lyase | 0.788±0.024 | 1.205±0.024 | 0.654 | 3.7295E–5 |
Phosphoribosylglycinamide formyltransferase | 0.875±0.047 | 1.137±0.057 | 0.769 | 0.0035588 |
Bifunctional purine biosynthesis protein | 0.785±0.010 | 1.218±0.023 | 0.644 | 2.3803E–6 |
Probable purine/pyrimidine phosphoribosyl transferase | 0.752±0.014 | 1.258±0.003 | 0.598 | 0.00044469 |
Phosphoribosylformylglycinamidine cyclo-ligase | 0.845±0.033 | 1.144±0.041 | 0.739 | 0.00055562 |
Phosphoribosylamine-glycine ligase | 0.770±0.003 | 1.234±0.021 | 0.624 | 6.5436E–7 |
N5-carboxyaminoimidazole ribonucleotide synthase | 0.860±0.054 | 1.145±0.029 | 0.751 | 0.00174152 |
Carbamoyl-phosphate synthase large chain | 0.852±0.002 | 1.146±0.004 | 0.744 | 1.1764E–8 |
Carbamoyl-phosphate synthase small chain | 0.823±0.032 | 1.168±0.017 | 0.704 | 0.000137371 |
Uridylate kinase | 0.857±0.007 | 1.129±0.009 | 0.759 | 1.0846E–6 |
Methylcrotonyl-CoA carboxylase, alpha-subunit (Biotin-containing) | 1.140±0.002 | 0.857±0.015 | 1.33 | 0.00129965 |
Putative 3-methylglutaconyl-CoA hydratase | 1.144±0.019 | 0.868±0.008 | 1.317 | 1.77453E–5 |
7,8-Dihydroneopterin aldolase | 0.866±0.036 | 1.136±0.080 | 0.762 | 0.0043613 |
Folylpolyglutamate synthetase | 0.810±0.017 | 1.193±0.034 | 0.679 | 4.2101E–5 |
30S ribosomal protein S1 | 0.718±0.009 | 1.270±0.002 | 0.565 | 0.000161656 |
30S ribosomal protein S2 | 0.755±0.012 | 1.250±0.028 | 0.604 | 3.1805E–6 |
30S ribosomal protein S3 | 0.674±0.006 | 1.326±0.022 | 0.508 | 1.7496E–7 |
30S ribosomal protein S4 | 0.697±0.014 | 1.293±0.002 | 0.539 | 0.0003421 |
30S ribosomal protein S5 | 0.731±0.013 | 1.289±0.017 | 0.567 | 7.1018E–7 |
30S ribosomal protein S6 | 0.744±0.019 | 1.269±0.025 | 0.586 | 4.0811E–6 |
30S ribosomal protein S7 | 0.688±0.012 | 1.304±0.030 | 0.527 | 1.4895E–6 |
30S ribosomal protein S8 | 0.717±0.010 | 1.285±0.016 | 0.558 | 3.1299E–7 |
30S ribosomal protein S9 | 0.694±0.018 | 1.301±0.027 | 0.534 | 2.4156E–6 |
30S ribosomal protein S10 | 0.683±0.010 | 1.320±0.009 | 0.517 | 1.1717E–7 |
30S ribosomal protein S11 | 0.693±0.010 | 1.293±0.026 | 0.536 | 8.5873E–7 |
30S ribosomal protein S12 | 0.675±0.015 | 1.327±0.021 | 0.509 | 8.0841E–7 |
30S ribosomal protein S13 | 0.695±0.004 | 1.310±0.009 | 0.53 | 1.1977E–8 |
30S ribosomal protein S14 | 0.641±0.005 | 1.368±0.021 | 0.469 | 8.5181E–8 |
30S ribosomal protein S15 | 0.71±0.0460 | 1.281±0.020 | 0.554 | 0.000100556 |
30S ribosomal protein S16 | 0.765±0.014 | 1.247±0.018 | 0.613 | 1.6871E–6 |
30S ribosomal protein S17 | 0.728±0.032 | 1.237±0.027 | 0.588 | 4.2612E–5 |
30S ribosomal protein S18 | 0.733±0.024 | 1.259±0.046 | 0.582 | 4.2153E–5 |
30S ribosomal protein S19 | 0.673±0.018 | 1.324±0.015 | 0.509 | 1.1598E–6 |
30S ribosomal protein S20 | 0.624±0.070 | 1.361±0.150 | 0.458 | 0.00104168 |
30S ribosomal protein S21 | 0.654±0.021 | 1.353±0.038 | 0.483 | 3.9375E–6 |
50S ribosomal protein L1 | 0.713±0.012 | 1.286±0.030 | 0.555 | 1.8159E–6 |
50S ribosomal protein L2 | 0.637±0.005 | 1.361±0.013 | 0.468 | 1.9918E–8 |
50S ribosomal protein L3 | 0.706±0.014 | 1.285±0.014 | 0.549 | 6.3875E–7 |
50S ribosomal protein L4 | 0.741±0.019 | 1.257±0.013 | 0.589 | 2.4412E–6 |
50S ribosomal protein L5 | 0.732±0.015 | 1.261±0.004 | 0.58 | 0.00046125 |
50S ribosomal protein L6 | 0.729±0.019 | 1.266±0.032 | 0.575 | 1.59459E–5 |
50S ribosomal protein L7/L12 | 0.762±0.021 | 1.242±0.068 | 0.614 | 0.000158888 |
50S ribosomal protein L9 | 0.726±0.029 | 1.278±0.016 | 0.568 | 1.987E–5 |
50S ribosomal protein L10 | 0.714±0.015 | 1.269±0.014 | 0.563 | 8.4667E–7 |
50S ribosomal protein L11 | 0.705±0.014 | 1.308±0.027 | 0.539 | 1.4216E–6 |
50S ribosomal protein L13 | 0.761±0.011 | 1.242±0.019 | 0.613 | 1.073E–6 |
50S ribosomal protein L14 | 0.741±0.014 | 1.258±0.011 | 0.589 | 7.0989E–7 |
50S ribosomal protein L15 | 0.691±0.009 | 1.314±0.035 | 0.526 | 1.388E–6 |
50S ribosomal protein L16 | 0.682±0.020 | 1.311±0.049 | 0.52 | 1.90508E–5 |
50S ribosomal protein L17 | 0.712±0.077 | 1.262±0.057 | 0.564 | 0.00106437 |
50S ribosomal protein L18 | 0.707±0.006 | 1.311±0.044 | 0.539 | 3.4752E–6 |
50S ribosomal protein L19 | 0.704±0.012 | 1.304±0.031 | 0.54 | 1.7169E–6 |
50S ribosomal protein L20 | 0.709±0.007 | 1.295±0.031 | 0.547 | 1.0428E–6 |
50S ribosomal protein L21 | 0.746±0.020 | 1.257±0.038 | 0.594 | 2.1688E–5 |
50S ribosomal protein L22 | 0.717±0.008 | 1.285±0.018 | 0.558 | 2.7836E–7 |
50S ribosomal protein L23 | 0.707±0.019 | 1.267±0.044 | 0.558 | 2.063E–5 |
50S ribosomal protein L24 | 0.718±0.014 | 1.276±0.033 | 0.563 | 3.4807E–6 |
50S ribosomal protein L25 | 0.759±0.013 | 1.238±0.015 | 0.613 | 1.0153E–6 |
50S ribosomal protein L27 | 0.662±0.015 | 1.341±0.014 | 0.494 | 5.3758E–7 |
50S ribosomal protein L28 | 0.730±0.008 | 1.271±0.039 | 0.574 | 3.8545E–6 |
50S ribosomal protein L29 | 0.652±0.034 | 1.329±0.021 | 0.491 | 2.06E–5 |
50S ribosomal protein L30 | 0.618±0.055 | 1.385±0.062 | 0.446 | 0.000158851 |
50S ribosomal protein L31 type B | 0.843±0.045 | 1.160±0.055 | 0.727 | 0.00152433 |
50S ribosomal protein L32 | 0.587±0.032 | 1.349±0.069 | 0.435 | 4.2315E–5 |
50S ribosomal protein L33 | 0.659±0.031 | 1.340±0.074 | 0.492 | 7.6482E–5 |
50S ribosomal protein L34 | 0.607±0.017 | 1.391±0.059 | 0.436 | 4.8286E–6 |
50S ribosomal protein L35 | 0.608±0.011 | 1.387±0.077 | 0.438 | 1.80613E–5 |
50S ribosomal protein L36 | 0.689±0.019 | 1.309±0.020 | 0.526 | 1.9408E–6 |
Ribosome modulation factor | 1.743±0.141 | 0.277±0.004 | 6.285 | 1.2295E–6 |
DNA primase | 0.827±0.052 | 1.179±0.028 | 0.702 | 0.00076473 |
Ribonuclease HII | 0.465±0.066 | 1.529±0.040 | 0.304 | 0.000159774 |
Replicative DNA helicase | 0.808±0.023 | 1.174±0.020 | 0.688 | 3.9244E–5 |
ATP-dependent RNA helicase | 0.796±0.011 | 1.189±0.019 | 0.669 | 2.4613E–6 |
ATP-dependent RNA helicase | 0.616±0.008 | 1.372±0.005 | 0.449 | 2.9544E–8 |
Poly(A) polymerase I | 0.854±0.005 | 1.147±0.045 | 0.744 | 0.0058823 |
Transcription termination factor | 0.781±0.009 | 1.210±0.013 | 0.645 | 5.4598E–7 |
DNA-directed RNA polymerase subunit alpha | 0.763±0.004 | 1.227±0.014 | 0.622 | 1.4663E–7 |
DNA-directed RNA polymerase subunit beta | 0.751±0.008 | 1.246±0.010 | 0.603 | 1.3205E–7 |
DNA-directed RNA polymerase subunit omega | 0.699±0.017 | 1.294±0.010 | 0.54 | 9.3888E–7 |
DNA-directed RNA polymerase subunit beta’ | 0.748±0.002 | 1.249±0.013 | 0.598 | 5.5309E–8 |
Regulatory protein, RsaL | 1.160±0.014 | 0.852±0.031 | 1.362 | 0.000141232 |
Transcriptional regulator, PtxS | 1.119±0.024 | 0.854±0.037 | 1.311 | 0.00062403 |
Two-component response regulator, CopR | 1.234±0.050 | 0.785±0.036 | 1.572 | 0.00020184 |
Two-component response regulator, PprB | 1.200±0.095 | 0.809±0.057 | 1.483 | 0.0030848 |
Notes:
P. aeruginosa treated with AgNP;
P. aeruginosa without AgNP treatment.
Abbreviations: AgNP, silver nanoparticle; PA, P. aeruginosa; TMT, Tandem Mass Tag.