Table 5. Log10 transformed least squares means (SEM) for serum concentrations of inflammatory cytokines and chemokines in cats with minimal or several oral disease undergoing dental treatment.
Analyte | Minimal | Severe | p value between groups at day 0 | p value between groups at day 6 | ||||
---|---|---|---|---|---|---|---|---|
Day 0 | Day 6 |
p value between days 0 and 6 |
Day 0 | Day 6 | p value between days 0 and 6 | |||
sFAS | 0.82 (0.17) | 0.74 (0.17) | 0.33 | 0.78 (0.17) | 0.66 (0.17) | 0.12 | 0.87 | 0.75 |
FLT-3L | 1.79 (0.06) | 1.81 (0.06) | 0.52 | 1.79 (0.06) | 1.79 (0.06) | 0.95 | 0.93 | 0.76 |
IFN-γ | 1.89 (0.14) | 1.87 (0.14) | 0.63 | 2.28 (0.14) | 2.16 (0.14) | 0.008 | 0.07 | 0.17 |
IL-1β | 1.17 (0.32) | 1.21 (0.32) | 0.66 | 1.56 (0.25) | 1.39 (0.25) | 0.022* | 0.37 | 0.68 |
IL-2 | 1.21 (0.22) | 1.03 (0.22) | 0.08 | 1.47 (0.22) | 1.41 (0.22) | 0.53 | 0.43 | 0.24 |
IL-4 | 2.04 (0.17) | 1.99 (0.17) | 0.28 | 2.57 (0.17) | 2.41 (0.17) | 0.0004 | 0.04* | 0.10 |
IL-6 | 1.95 (0.15) | 1.91 (0.15) | 0.28 | 2.07 (0.15) | 1.93 (0.15) | 0.0006 | 0.94 | 0.94 |
IL-8 | 1.39 (0.09) | 1.24 (0.09) | 0.003 | 1.59 (0.09) | 1.46 (0.09) | 0.006 | 0.11 | 0.08 |
IL-12p40 | 2.52 (0.08) | 2.62 (0.08) | 0.005 | 2.52 (0.08) | 2.66 (0.08) | 0.0002 | 0.99 | 0.72 |
IL-13 | 1.35 (0.15) | 1.28 (0.15) | 0.11 | 1.34 (0.14) | 1.26 (0.14) | 0.03* | 0.97 | 0.90 |
IL-18 | 2.00 (0.10) | 2.02 (0.11) | 0.71 | 2.12 (0.10) | 1.99 (0.10) | 0.031* | 0.41 | 0.81 |
KC | 0.68 (0.32) | 0.89 (0.33) | 0.49 | 1.02 (0.28) | 1.58 (0.26) | 0.033* | 0.44 | 0.13 |
MCP-1 | 2.89 (0.13) | 2.82 (0.13) | 0.11 | 3.07 (0.13) | 2.97 (0.13) | 0.007 | 0.48 | 0.48 |
PDGF-BB | 2.76 (0.13) | 2.77 (0.13) | 0.93 | 2.98 (0.14) | 2.75 (0.14) | 0.015* | 0.28 | 0.94 |
RANTES | 1.51 (0.07) | 1.48 (0.07) | 0.44 | 1.54 (0.07) | 1.43 (0.07) | 0.003 | 0.75 | 0.58 |
SCF | 2.07 (0.07) | 2.05 (0.07) | 0.69 | 2.35 (0.07) | 2.22 (0.07) | 0.0003 | 0.10 | 0.006 |
SDF-1 | 2.86 (0.09) | 2.91 (0.09) | 0.39 | 2.91 (0.10) | 2.84 (0.10) | 0.85 | 0.77 | 0.61 |
TNF-α | 1.40 (0.45) | 1.50 (0.45) | 0.57 | 2.24 (0.39) | 1.97 (0.39) | 0.11 | 0.21 | 0.48 |
* not significant after adjustment.