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. 2019 Mar 1;14(3):e0213195. doi: 10.1371/journal.pone.0213195

Table 5. Log10 transformed least squares means (SEM) for serum concentrations of inflammatory cytokines and chemokines in cats with minimal or several oral disease undergoing dental treatment.

Analyte Minimal Severe p value between groups at day 0 p value between groups at day 6
Day 0 Day 6 p value between
days 0 and 6
Day 0 Day 6 p value between days 0 and 6
sFAS 0.82 (0.17) 0.74 (0.17) 0.33 0.78 (0.17) 0.66 (0.17) 0.12 0.87 0.75
FLT-3L 1.79 (0.06) 1.81 (0.06) 0.52 1.79 (0.06) 1.79 (0.06) 0.95 0.93 0.76
IFN-γ 1.89 (0.14) 1.87 (0.14) 0.63 2.28 (0.14) 2.16 (0.14) 0.008 0.07 0.17
IL-1β 1.17 (0.32) 1.21 (0.32) 0.66 1.56 (0.25) 1.39 (0.25) 0.022* 0.37 0.68
IL-2 1.21 (0.22) 1.03 (0.22) 0.08 1.47 (0.22) 1.41 (0.22) 0.53 0.43 0.24
IL-4 2.04 (0.17) 1.99 (0.17) 0.28 2.57 (0.17) 2.41 (0.17) 0.0004 0.04* 0.10
IL-6 1.95 (0.15) 1.91 (0.15) 0.28 2.07 (0.15) 1.93 (0.15) 0.0006 0.94 0.94
IL-8 1.39 (0.09) 1.24 (0.09) 0.003 1.59 (0.09) 1.46 (0.09) 0.006 0.11 0.08
IL-12p40 2.52 (0.08) 2.62 (0.08) 0.005 2.52 (0.08) 2.66 (0.08) 0.0002 0.99 0.72
IL-13 1.35 (0.15) 1.28 (0.15) 0.11 1.34 (0.14) 1.26 (0.14) 0.03* 0.97 0.90
IL-18 2.00 (0.10) 2.02 (0.11) 0.71 2.12 (0.10) 1.99 (0.10) 0.031* 0.41 0.81
KC 0.68 (0.32) 0.89 (0.33) 0.49 1.02 (0.28) 1.58 (0.26) 0.033* 0.44 0.13
MCP-1 2.89 (0.13) 2.82 (0.13) 0.11 3.07 (0.13) 2.97 (0.13) 0.007 0.48 0.48
PDGF-BB 2.76 (0.13) 2.77 (0.13) 0.93 2.98 (0.14) 2.75 (0.14) 0.015* 0.28 0.94
RANTES 1.51 (0.07) 1.48 (0.07) 0.44 1.54 (0.07) 1.43 (0.07) 0.003 0.75 0.58
SCF 2.07 (0.07) 2.05 (0.07) 0.69 2.35 (0.07) 2.22 (0.07) 0.0003 0.10 0.006
SDF-1 2.86 (0.09) 2.91 (0.09) 0.39 2.91 (0.10) 2.84 (0.10) 0.85 0.77 0.61
TNF-α 1.40 (0.45) 1.50 (0.45) 0.57 2.24 (0.39) 1.97 (0.39) 0.11 0.21 0.48

* not significant after adjustment.