Fig 11. Proposed transition mechanism starting from the dark state of VVD as state 3.

Commu. B may function as a switch to be turned on first (State 3 to 2) and lead the conformational change of Commu. A (N-terminus) (State 2 to 7). Commu. A and B are illustrated in blue for State 3, green for State 2, and red for State 7.