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Associations between residuals of regressing [18F]FEPPA VT on TSPO genotype and residuals of regressing GABA+/H2O levels in medial prefrontal cortex (mPFC) on TSPO genotype in people at clinical high risk (CHR) for psychosis (r = −0.49, p = 0.008) and healthy volunteers (HV; r = −0.53, p = 0.053). GABA+ = γ-aminobutyric acid plus macromolecule; TSPO = translocator protein 18 kDa; VT = total distribution volume.
