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. Author manuscript; available in PMC: 2020 Mar 15.
Published in final edited form as: Am J Cardiol. 2018 Dec 18;123(6):874–881. doi: 10.1016/j.amjcard.2018.11.057

Table 1.

Baseline characteristics and incident clinical outcomes according to the duration of daily sleep*

 Variable All (N=2846) Short (< 6.5 H) (N=1119) Normal (≥ 6.5 to < 7.5 H) (N=741) Long (≥ 7.5 H) (N=986) Overall P-value P-value for pairwise comparison
Normal vs short Normal vs long Short vs long
Age (years)  64 ± 13 62 ± 12 64 ± 12 66 ± 13 <0.001 0.006 <0.001 <0.001
Women 1071 (38%) 472 (42%) 254 (34%) 345 (35%) <0.001 0.001 0.76 0.001
Black  642 (23%) 372 (33%) 124 (17%) 146 (15%) <0.001 <0.001 0.28 <0.001
Body mass index (kg/m2)  30 ± 6 31 ± 7 30 ± 6 29 ± 6 <0.001 <0.001 0.61 <0.001
Hypertension 2427 (85%) 968 (87%) 624 (84%) 836 (85%) 0.37 0.20 0.80 0.27
Diabetes mellitus 1064 (38%) 441 (40%) 258 (35%) 365 (37%) 0.13 0.05 0.34 0.27
Hyperlipidemia 2139 (75%) 838 (75%) 535 (72%) 766 (78%) 0.04 0.17 0.01 0.17
Smoker 2067 (73%) 800 (72%) 522 (70%) 745 (76%) 0.03 0.63 0.02 0.04
Prior MI  642 (23%) 241 (22%) 149 (21 %) 252 (26%) 0.02 0.46 0.01 0.04
Heart failure 987 (35%) 412 (37%) 230 (31%) 345 (35%) 0.04 0.01 0.09 0.38
Ejection fraction (%) 53 ± 12 53 ± 13 54 ± 11 52 ± 13 0.01 0.04 0.02 0.88
Gensini score, points 86 [2,240] 80 [0,234] 85 [2,244] 112 [4,256] 0.07 0.91 0.83 0.06
Obstructive CAD 2082 (82%) 792 (81%) 542 (81%) 748 (84%) 0.20 0.68 0.24 0.08
Acute MI at enrollment 228 (8%) 90 (8%) 60 (8%) 78 (8%) 0.99 0.97 0.89 0.97
Revascularization at enrollment 941 (33%) 373 (33%) 253 (34%) 315 (32%) 0.61 0.72 0.34 0.50

All-cause death 412 (15%) 166 (15%) 81 (11%) 165 (17%) 0.003 0.02 0.001 0.05
Cardiovascular death 251 (9%) 111 (10%) 50 (7%) 90 (9%) 0.06 0.02 0.07 0.77
Myocardial infarction 107 (4%) 42 (4%) 22 (3%) 43 (4%) 0.32 0.36 0.13 0.99
Coronary revascularization 587 (21%) 236 (21%) 150 (20%) 201 (20%) 0.88 0.66 0.94 0.73
Stroke 68 (2%) 25 (2%) 18 (2%) 25 (3%) 0.90 0.78 0.89 0.65
*

Values are mean (SD), median [25th and 75th interquartile range], or n (%).

Defined by physician diagnosis in medical charts

Obstructive coronary artery disease (CAD) is defined by the presence of ≥50% obstructive lesion in any of the major epicardial vessels on coronary angiography at enrollment.

Abbreviations: MI = myocardial infraction; CAD = coronary artery disease