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(A) Oxygen levels in different embryonic development stages. (B) Measures of in vivo O2 levels in different tissues ([Fitzgerald et al., 1999; Simon and Keith, 2008; Mohyeldin et al., 2010; Wang and Zhao, 2010; Abdollahi et al., 2011; Carreau et al., 2011; Ortega et al., 2017]).
