Table 1.
Mean relative abundance of different taxa at phylum level.
| Stage | Phylum | Control | Ceftriaxone | Vancomycin | TMC3115 | Ceftri + TMC3115 | Vanco + TMC3115 |
|---|---|---|---|---|---|---|---|
| PND21 | Actinobacteria | 0.02% | 1.72%** | <0.01% | 0.08% | 12.36%** | 0.14% |
| Bacteroidetes | 65.71% | 5.38%*** | 0.15%** | 78.26%* | 1.08%*** | 0.11%** | |
| Firmicutes | 27.39% | 71.01%** | 29.2% | 12.34%** | 83.39%** | 28.77% | |
| Proteobacteria | 5.60% | 21.17%* | 70.64%*** | 8.92% | 3.00% | 70.98%*** | |
| PND56 | Actinobacteria | 0.18% | 0.05% | 0.36% | 0.24% | <0.01% | <0.01% |
| Bacteroidetes | 79.33% | 43.30%*** | 58.55%*** | 38.33%*** | 63.96%*** | 57.33%*** | |
| Deferribacteres | 0.04% | 0.01% | 1.62%* | 0.21% | <0.01% | 0.04% | |
| Firmicutes | 15.52% | 48.29%** | 37.41%** | 57.20%** | 25.58%* | 28.64%** | |
| Proteobacteria | 3.53% | 4.18% | 1.72% | 2.47% | 6.23% | 9.16%** | |
| Verrucomicrobia | 0.80% | 4.03% | 0.01% | 0.35% | 3.57%* | 4.77%* |
n = 4/group; *p < 0.05, **p < 0.01, ***p < 0.001, comparing with control. TMC3115, Bifidobacterium bifidum TMC3115; Ceftri, Ceftriaxone; Vanco, Vancomycin; PND, postnatal day.