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. 2019 Mar 1;9:3231. doi: 10.1038/s41598-019-39771-5

Figure 5.

Figure 5

Electrophysiology reveals differences between CK and Rd potentiation of P2X7. (A) HEK-hP2X7 and central vestibule mutants were voltage clamped at −60 mV and either ATP alone (100 µM), ATP + CK (10 µM), or ATP + Rd (10 µM) was rapidly applied for 5 seconds prior to wash off. Traces are representative of 5–9 cells. (B) Summary of normalised current amplitudes expressed as pA/pF (n = 5–9 cells). (C) Potentiation of ATP responses by CK and Rd expressed as fold potentiation (normalised to ATP alone).