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. 2019 Mar 1;9:3209. doi: 10.1038/s41598-019-39965-x

Figure 1.

Figure 1

EGFR mutations and exon distribution. EGFR protein structure highlighting the tyrosine kinase domain (red), which is the hotspot region (red) for the EGFR mutations with predictive value. All resistance and sensitizing mutations detected in the present series of Brazilian lung adenocarcinoma are presented. *Controversial results in the literature.