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. 2019 Mar 1;9:3306. doi: 10.1038/s41598-019-39778-y

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effects of fenofibrate on the expression of cell cycle regulators in Hep3B cells. Hep3B cells were incubated with 0.1% DMSO or with 50, 75 or 100 µM fenofibrate for 24 h. Cell lysates were analyzed by SDS-PAGE (10% for cyclin A, cyclin B and cyclin E, 12% for β-actin, 13% for Cdk1, Cdk2, Cdk4 and cyclin D1 and 14% for p21), and then probed with primary antibodies followed by secondary antibodies. Results are representative of three independent experiments performed in triplicate. All of full-length gels and blots are included in Supplementary Fig. 4.