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. 2019 Mar 1;9:3199. doi: 10.1038/s41598-019-39840-9

Table 2.

Positive IFN-γ responses to norovirus (NoV) and to rotavirus (RV) at different age.

Donor ≤12 mo 2–3 y 4 y
NoV GI.3/GII.4 RV NoV GI.3/GII.4 RV NoV GI.3/GII.4 RV
1a −/− −/− N/A +/−
2 −/− −/− + N/A N/A
3b −/− −/− +/+ +
4 −/− −/+ + +/− +
5a +/+ + +/+ + +/+ +
6 −/+ + N/A N/A N/A N/A
7 −/+ + +/+ + +/− +
8 −/+ + +/+ + +/+ +
9 −/+ + N/A/+ + N/A/— N/A
10 −/− + −/+ + +/+ +

aReceived RV vaccine (3 doses) before 6 months of age.

bReceived RV vaccine (1 dose) before 3 months of age.

−, a negative readout (below the cut-off level) in ELISPOT IFN-γ assay. +, a positive readout (above the cut-off level) in ELISPOT IFN-γ assay. N/A, not available.