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. 2019 Mar 1;9:3248. doi: 10.1038/s41598-019-39011-w

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Comparative graph showing effects of maximum concentrations of antioxidants, (a) ascorbic acid (80 µM), (b) D3T (100 µM), and (c) BHA (100 µM) on three transfected HEK 293 cells with different genetic constructs, using Eq. 1. Reported values are the average ± SD of three independent experiments and they indicate better induction of PPR2 when affected by ascorbic acid. ***P-value < 0.001 by Two- way ANOVA data analyzing.