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. 2019 Mar 1;9:3289. doi: 10.1038/s41598-019-39772-4

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Analysis of the circulating endothelial cells. (A) A cytogram of CD34 versus CD133 expression gated from the extended lymphocyte gate (Fig. 1A). (B) VEGFR2 receptor expression by double-positive progenitor cells. (C) Dynamics of the changes in the total number of cEPCs in septic shock patients. Cell counts between healthy controls and septic shock patients were compared using Mann-Whitney U test and the statistical significance was marked as follows: *p < 0.05. Cell counts between days 1 and 3 was compared by the Wilcoxon signed-rank test which did not reveal significant differences.