Cell numbers of chondrocytes after 24-hour incubation with different dilutions of the different drugs determined by lactate dehydrogenase (LDH) assay. a) Dilution 1:2, b) Dilution 1:10, c) Dilution 1:100. Results are presented as mean and sd for each drug. For all dilutions, one-way analysis of variance (ANOVA) showed significant differences between the groups (p-value < 0.0001). For post hoc testing, * (p-value < 0.05), † (p-value < 0.01) and ‡ (p-value < 0.001) indicate statistical significance (non-paired t-test) towards normal saline.