Table 1.
WT |
Kcna1−/− |
|||
---|---|---|---|---|
Left Atrium (n = 8/4) | Right Atrium (n = 8/5) | Left Atrium (n = 6/4) | Right Atrium (n = 4/3) | |
APD30, ms | 5.6 ± 0.8 | 5.2 ± 0.6 | 6.3 ± 0.8 | 6.2 ± 0.7 |
APD50, ms | 8.0 ± 1.1 | 7.9 ± 0.7 | 11.0 ± 1.8 | 8.6 ± 1.0 |
APD90, ms | 49.9 ± 2.6 | 46.7 ± 2.9 | 70.1 ± 3.1* | 102.6 ± 11.1†,‡ |
Values are means ± SE. APD30, APD50, and APD90, action potential duration at 30%, 50%, and 90% of repolarization, respectively. Sample numbers (n) indicate myocytes per mouse. WT, wild type.
P < 0.01 vs. WT left atrium (Student’s unpaired t-test);
P < 0.01 vs. WT right atrium (Student’s unpaired t-test);
P < 0.01 vs. Kcna1−/− left atrium (Student’s unpaired t-test).