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. 2018 Dec 21;316(2):E286–E292. doi: 10.1152/ajpendo.00341.2018

Fig. 3.

Fig. 3.

Signal transducer and activator of transcription 3 (STAT3) inhibitor Stattic treatment decreased leptin in obese mice during sepsis. Plasma leptin was measured in obese and nonobese mice with vehicle or Stattic treatment at 0 and 18 h after cecal ligation and puncture (CLP). Data represent means and SD and were analyzed by two-way ANOVA. *P ≤ 0.05 vs. 0-h CLP by diet; #P ≤ 0.05 vs. nonobese mice within treatment group; @P ≤ 0.05 vs. vehicle by diet. Open bars, nonobese; filled bars, obese (n = 7–10/group).