Fig. 3.

Bcl-2-associated athanogene 3 (Bag3) P209L knockin (KI) mutant mice display normal cardiac function. A−E: echocardiographic analysis showing fractional shortening (FS; A), left ventricular internal diameter at diastole (LVIDd; B), left ventricular internal diameter at systole (LVIDs; C), left ventricular posterior wall thickness at diastole (LVPWd; D), and interventricular septum diameter at diastole (IVSd; E) in wild-type (+/+) control (n = 9) and heterozygous (m/+) (n = 7) and homozygous (m/m) (n = 13) Bag3 P209L-KI mutant mice at 4, 11, and 16 mo of age. Data are presented as means ± SE.