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. 2018 Nov 21;316(2):H298–H310. doi: 10.1152/ajpheart.00185.2018

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Fig. 4. — Effects of ouabain and SEA0400 on femoral artery cytosolic Ca²⁺ concentration ([Ca²⁺]_CYT) and diameter. [Ca²⁺]_CYT increase (Δ[Ca²⁺]_CYT; A) and vasoconstriction [diameter decrease, as %passive diameter (PD); B] induced by a 15-min superfusion with 10 μM ouabain as well as the effects of 0.3 μM SEA0400 (15-min pretreatment before ouabain) on these changes. Ouabain-induced, SEA0400-sensitive effects were amplified in transgenic (TG) mouse arteries. Values are means ± SE. Statistics were by a paired t-test. #P < 0.05 vs. ouabain alone. Numbers of mice are in parentheses.