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. 2018 Nov 21;316(2):H298–H310. doi: 10.1152/ajpheart.00185.2018

Fig. 5.

Fig. 5.

The acute and chronic angiotensin II (ANG II)-induced blood pressure elevation is augmented in transgenic (TG) mouse arteries. A: mean blood pressure (24-h MBP) in awake, mobile smooth muscle-specific NCX1 knockout mice (SM-NCX1-KO; KO), control (Ctrl) mice, and TG mice that overexpress NCX1 specifically in smooth muscle (SM-NCX1-TG; TG) mice infused with saline or ANG II (400 ng·kg−1·min−1 sc) for 3 wk. B: increases in aortic MBP (ΔMBP) induced by acute intravenous infusion of 30 or 300 ng/kg ANG II in lightly anesthetized KO, Ctrl, and TG mice. Values are means ± SE. Statistics were by two-way ANOVA. *P < 0.05 and ***P < 0.001 for the pairs indicated. NS, nonsignificant. Numbers of mice are in parentheses.