Fig. 3.

A: plasma copeptin response during an oral glucose tolerance test (n = 16; trial F = 14.193, P = 0.002; time F = 1.285, P = 0.282; trial × time F = 1.396, P = 0.261). B: plasma copeptin response during an oral glucose tolerance test, with those who had muscle biopsies on both trials (n = 7) separated from those who had no biopsies on either trial (n = 7). For those who had biopsies a fasted blood sample was taken before the biopsy (time point “Pre-biopsy”) and after the biopsy immediately before the glucose was ingested (time point “0”), and for those who did not have biopsies only 1 fasted sample was taken (time point “0”). *P < 0.050, **P < 0.010 comparing hypohydrated trial arm (HYPO) and rehydrated trial arm (RE) (trial effect) after Bonferroni adjustment for multiple comparisons. Error bars show normalized 95% confidence intervals.