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. 2018 Jan 4;126(2):354–362. doi: 10.1152/japplphysiol.00199.2016

Table 1.

Echocardiographic findings of three groups at baseline, after 4 and 8 wk

Control
Exercise
TAC
Baseline 4 wk P 8 wk P Baseline 4 wk P 8 wk P Baseline 4 wk P 8 wk P
HR, beats/min 415 ± 41 410 ± 20 NS 404 ± 20 NS 425 ± 47 419 ± 35 NS 412 ± 35 NS 402 ± 39 411 ± 22 NS 421 ± 22 NS
PW, mm 0.66 ± 0.03 0.7 ± 0.05 NS 0.70 ± 0.04 NS 0.66 ± 0.05 0.75 ± 0.03 0.002 0.81 ± 0.03 0.001 0.63 ± 0.05 0.93 ± 0.04 0.001 1.13 ± 0.06 0.001
LVEDD, mm 4.3 ± 0.2 4.4 ± 0.3 NS 4.4 ± 0.2 NS 4.1 ± 0.1 4.7 ± 0.2 0.002 4.7 ± 0.4 0.002 4.5 ± 0.2 4.47 ± 0.3 NS 4.47 ± 0.3 NS
RWT, mm 0.31 ± 0.02 0.31 ± 0.04 NS 0.31 ± 0.02 NS 0.32 ± 0.02 0.35 ± 0.03 NS 0.39 ± 0.03 0.01 0.31 ± 0.02 0.41 ± 0.03 0.002 0.5 ± 0.06 0.001
LV area, mm2 13.8 ± 0.6 13.9 ± 0.7 NS 13.9 ± 0.7 NS 13.5 ± 0.7 16.1 ± 0.6 0.002 19.7 ± 0.9 0.001 14.4 ± 0.4 13.9 ± 0.6 NS 13.9 ± 0.6 NS
EF, % 60.2 ± 0.9 60.3 ± 0.4 NS 59.1 ± 0.8 NS 58.0 ± 0.2 59.3 ± 0.3 NS 60.5 ± 0.5 NS 59.4 ± 0.6 53.8 ± 0.5 NS 44.6 ± 0.9 0.001
E/A 1.89 ± 0.8 1.91 ± 0.6 NS 1.92 ± 0.9 NS 1.91 ± 0.6 2.2 ± 0.7 NS 2 ± 0.9 NS 1.9 ± 0.7 2.1 ± 0.5 NS 2.9 ± 0.8 0.001
E′/A′ 1.45 ± 0.2 1.64 ± 0.3 NS 1.61 ± 0.3 NS 1.46 ± 0.3 1.65 ± 0.4 NS 1.55 ± 0.3 NS 1.6 ± 0.6 1.57 ± 0.2 NS 1.5 ± 0.5 NS
E/E′ 32.3 ± 5.2 32.5 ± 6.1 NS 32.8 ± 3.8 NS 31.2 ± 4.9 30.4 ± 5.7 NS 28.2 ± 5.0 NS 32.6 ± 3.7 33.5 ± 6.3 NS 37 ± 6.2 0.002
s′, mm/s 20.1 ± 4.2 20.7 ± 3.1 NS 20.9 ± 5.1 NS 19.6 ± 4.1 27.8 ± 5.4 0.046 29.2 ± 2.3 0.001 21 ± 3.6 18.7 ± 4.6 NS 17 ± 4.2 0.04

Values are means ± SE. HR, heart rate; PW, posterior wall; LVEDD, left ventricular end-diastolic dimension; RWT, relative wall thickness; LV, left ventricle; EF, ejection fraction; NS, nonsignificant.