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. 2018 Dec 20;126(2):502–510. doi: 10.1152/japplphysiol.00421.2018

Fig. 6.

Fig. 6.

A: endothelium-dependent relaxation (EDR) in the femoral artery in normal-salt (NS) rats in response to acetylcholine (ACh) with and without addition of the superoxide dismutase mimetic TEMPOL. B: EDR in the femoral artery in high-salt (HS) rats in response to ACh with and without the addition of TEMPOL. C: EDR in the femoral artery in NS rats in response to ACh with and without addition of the NADPH oxidase inhibitor apocynin (APO). D: EDR in femoral artery in HS rats in response to ACh with and without the addition of the NADPH oxidase inhibitor APO. E: EDR in the femoral artery in NS rats in response to ACh with and without addition of TEMPOL + APO (T/A). F: EDR in femoral artery in HS rats in response to ACh with and without the addition of T/A. G: maximal relaxation with and without the addition of TEMPOL, APO, or T/A. H: area under the curve (AUC) with and without the addition of TEMPOL, APO, or T/A. Values are means ± SE; n: NS = 12, NS-voluntary wheel running (VWR) = 13, HS = 14, HS-VWR = 12. Data analysis was performed with a (4 × 3) 2-way repeated-measures ANOVA.*vs. HS, §vs. respective control group (P < 0.05).