Table 1.

Animal characteristics

	NS (n = 12)		NS-VWR (n = 13)		HS (n = 14)		HS-VWR (n = 12)
	Baseline	Week 6	Baseline	Week 6	Baseline	Week 6	Baseline	Week 6
Body mass, g	271 ± 6	382 ± 10*	275 ± 7.8	377 ± 10*	274 ± 7.8	384 ± 7*	279 ± 6.5	377 ± 6.4*
Heart mass, g/BW		0.36 ± 0.01		0.39 ± 0.02		0.36 ± 0.01		0.35 ± 0.01
Serum sodium, mmol/l	136 ± 0.7	139 ± 0.6*	135 ± 0.8	139 ± 0.4*	138 ± 0.6	140 ± 0.4*	138 ± 0.5	140 ± 0.5*
Urinary sodium excretion, mmol·l−1·24 h−1	388 ± 57	457 ± 66	396 ± 68	610 ± 90	419 ± 66	1,897 ± 362*†‡	547 ± 79	1,813 ± 283*†‡
MAP, mmHg	103 ± 4	105 ± 3	107 ± 3	106 ± 3	106 ± 3	108 ± 3	106 ± 3	108 ± 3

Values are means ± SE for n animals. BW, body weight; HS, high salt; MAP, mean arterial pressure; NS, normal salt; VWR, voluntary wheel running.

^*vs. baseline,

^†vs. NS 6 wk,

^‡vs. NS-VWR 6 wk (P < 0.05).