Table 2.
Calculated Areas Under the Curve for the 3-H Profile
| PL | BPA-4 | BPA-50 | P Value | |
|---|---|---|---|---|
| BPA AUC (ng/mL · min) | 56 (12, 258)a | 571 (126, 2580)b | 10,676 (2319, 49,151)c | <0.001 |
| Glucose AUC (mmol/L · min) | 1088 (978, 1210)a | 1068 (960, 1188)a,b | 998 (897, 1110)b | 0.017 |
| Insulin AUC (μIU/mL · min) | 6036 (5263, 6922)a | 6044 (5271, 6932)a | 5120 (4464, 5871)b | 0.011 |
| C-peptide AUC (pmol/L · min) | 201,637 (171,134, 237,576)a | 210,018 (178,247, 247,451)a | 181,016 (153,632, 213,280)b | 0.003 |
| Proinsulin AUC (pmol/L · min) | 3143 (2510, 3935) | 3078 (2458, 3854) | 3339 (2667, 4181) | 0.749 |
| Estradiol AUC (pg/mL · min) | 8744 (5161, 14,814) | 9608 (5621, 16422) | 8913 (5261, 15,102) | 0.873 |
| TG AUC (mmol/L · min) | 172 (137, 217) | 160 (127, 201) | 165 (131, 208) | 0.612 |
Data are geometric mean (95% CI).
Abbreviations: AUC, area under the curve; Estradiol, 17β-estradiol; TG, triglyceride.
a,b,cWithin each row, geometric means not sharing a similar letter are significantly different (Tukey adjustment, P < 0.05).