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. 2019 Mar 1;15:70. doi: 10.1186/s12917-019-1814-z

Table 3.

Specificity and 95% Wilson’s confidence intervals of the P22 ELISA for detecting antibodies against the Mycobacterium tuberculosis complex at two cut-off points in different host species from Norway (A) and Spain (B)

Cut-off 100% Cut-off 150%
Species N° of animals Na Spb Na Spb
A)
 Cattle 500 20* 96 (93.9–97.4) 3 99.4 (98.3–99.8)
 Goat 100 22* 78 (68.9–85) 3* 97 (91.6–99)
 Sheep 100 4 96 (90.2–98.4) 0 100 (96.3–100)
 Pig 100 0 100 (96.3–100) 0 100 (96.3–100)
 Total 800
B)
 Cattle 1014 76* 92.50 (90.7–94) 20 98 (97–98.7)
 Goat 123 85* 30.9 (23.4–39.5) 54* 56.1 (47.3–64.6)
 Sheep 394 22 94.4 (91.7–96.3) 7 98.23 (96.4–99.1)
 Pig 100 0 100 (86.2–100) 0 100 (86.2–100)
 Total 1631

aNumber of positive animals

b95% Confidence interval for specificity

*Significant difference (p < 0.05) in the proportion of negative animals of each species between Norway and Spain