Table 2.
Genes encoding proteins involved in hydrogen and pyruvate metabolism that are differentially regulated in OXY and NAO S. salmonicida cells
| Protein name | Abbr. In Fig. 2 | OrthoMCL group | Spironucleus salmonicida | Giardia intestinalis WB | Giardia intestinalis GS | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Gene ID (SS50377_) | NCBI accession | OXY LFCa | NAO LFCa | Gene ID (GL50803_) | LFCb | Gene ID (GL50581_) | LFCb | |||
| [2Fe-2S] Ferredoxin 1 | FER | OG5_126994 | 14776 | EST45204.1 | 3.0 | 1.8 | 27266 | - | 3971 | - |
| [2Fe-2S] Ferredoxin 2 | FER | OG5_126994 | 11457 | EST48363.1 | - | 1.1 | 27266 | - | 3971 | - |
| Pyruvate:ferredoxin oxidoreductase 1 | PFO | OG5_129721 | 12338 | EST47643.1 | 4.1 | 1.7 | 114609 | 0.8 | 1047 | - |
| Pyruvate:ferredoxin oxidoreductase 2 | PFO | OG5_129721 | 18347 | EST42040.1 | 1.6 | - | 114609 | 0.8 | 1047 | - |
| Pyruvate:ferredoxin oxidoreductase 3 | PFO | OG5_129721 | 15961 | EST44237.1 | 1.4 | - | 114609 | 0.8 | 1047 | - |
| Pyruvate:ferredoxin oxidoreductase 4 | PFO | OG5_129721 | 12070 | EST47847.1 | - 1.8 | - | 114609 | 0.8 | 1047 | - |
| Pyruvate:ferredoxin oxidoreductase 5 | PFO | OG5_129721 | 10765 | EST48995.1 | 2.0 | 1.2 | 114609 | 0.8 | 1047 | - |
| [FeFe]-hydrogenase 4 | HYDA | OG5_127303 | 15891 | EST44288.1 | - | 1.9 | 6304 | - | 4021 | - |
| [FeFe]-hydrogenase 6 | HYDA | OG5_127303 | 10025 | EST49607.1 | - 3.0 | - | 6304 | - | 4021 | - |
| HYDA assembly protein HydE | HYDE | OG5_155498 | 14972 | EST44954.1 | 1.5 | 1.5 | n/a | n/a | n/a | n/a |
| HYDA assembly protein HydF | HYDF | OG5_168779 | 16918 | EST43253.1 | 2.8 | - | n/a | n/a | n/a | n/a |
| HYDA assembly protein HydG | HYDG | OG5_139637 | 17876 | EST42561.1 | 3.3 | 1.4 | n/a | n/a | n/a | n/a |
| Acetyl-CoA synthetase | ACS | OG5_131604 | 10513 | EST49290.1 | 1.5 | 1.4 | 13608 | 1.2 | 1568 | - |
| Flavodoxin | FLD | OG5_127162 | 11261 | EST48648.1 | - | - 1.1 | 15897 | - | 735 | - |
| Flavodoxin | FLD | OG5_127162 | 16443 | EST43822.1 | - | - 1.2 | 15897 | - | 735 | - |
| Flavodoxin | FLD | OG5_127162 | 11221 | EST48609.1 | - | 1.4 | 15897 | - | 735 | - |
| Flavodoxin | FLD | OG5_127162 | 11235 | EST48623.1 | 1.0 | - | 15897 | - | 735 | - |
| Flavodoxin | FLD | OG5_127162 | 16430 | EST43810.1 | 3.7 | 1.7 | 15897 | - | 735 | - |
| Flavodoxin | FLD | OG5_127162 | 15167 | EST45144.1 | 3.9 | 1.3 | 15897 | - | 735 | - |
| Flavodoxin | FLD | OG5_127162 | 13883 | EST45907.1 | 7.2 | 5.9 | 15897 | - | 735 | - |
a|Log2 (fold change)| > 1.0 with q-values < 0.05 from this study; '-' indicates not significant changes
b|Log2 (fold change)| > 0.7 with p-values < 0.05 from [25]; '-' indicates not significant changes
n/a indicates that the gene was not found in Giardia intestinalis