Geh blunts the S. aureus-induced proinflammatory response in vivo. (A) MCP1, TNF, and KC (pg/mL) levels in hearts 24 h postinfection with WT, Δgeh, and Δgeh + geh strains (n = 4). (B) MCP1, CCL3, and CCL4 (pg/mL) levels in spleens 24 h postinfection with the indicated strains (n = 4). (C) MPO activities (mU/mg) in hearts and spleens 24 h postinfection with the indicated strains [n = 8 (WT and Δgeh), n = 4 (Δgeh + geh)]. mU, milliunits. Mean ± SD is shown. Statistical significance was determined using one-way ANOVA with Bonferroni’s post hoc test. *P < 0.05; **P < 0.01.