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Global fitting results to all of the NMR data on httNTQ7 using a grid search on the value of the rate constant k−2 for the dissociation of tetramers (P4) into dimers (P2). The panels show the dependence of χ2 and the optimized values of the rate constants and equilibrium dissociation constants as a function of fixed values of k−2. The gray shaded region represents the range of k−2 where χ2 is at a plateau minimum.
