. Author manuscript; available in PMC: 2019 Sep 26.

Published in final edited form as: J Am Chem Soc. 2018 Sep 13;140(38):12137–12143. doi: 10.1021/jacs.8b06961

Table 1.

Minimum inhibitory concentrations and therapeutic indices of P5 PNPs against multiple uropathogenic clinical isolate bacterial strains. Therapeutic indices are calculated with respect to red blood cells.

Strain	Species	MIC (nM)	TI (HC₅₀/MIC)
CD-23	P, aeruginosa	64	~2,500
CD-1006	P, aeruginosa	128	~1,250
CD-489	S. aureus - MRSA	64	~2,500
CD-2	E. coli	64	~2,500
CD-3	E. coli	64	~2,500
CD-19	E. coli	64	~2,500
CD-549	E. coli	128	~1,250
CD-496	E. coli	128	~1,250
CD-866	E. cloacae complex	128	~1,250
CD-1412	E. cloacae complex	128	~1,250
CD-1545	E. cloacae complex	128	~1,250