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. Author manuscript; available in PMC: 2019 Mar 2.
Published in final edited form as: Nanoscale. 2016 Dec 2;9(1):288–297. doi: 10.1039/c6nr07353k

Fig. 2.

Fig. 2

Dynamics of cell-binding and internalization of single IgG–PEG Janus particles as well as clusters of IgG–PEG Janus particles. Bright-field images showing the rotation of a 1.6 μm IgG–PEG Janus particle during cell binding (a) and the clustering of 1.2 μm IgG–PEG Janus particles (b) during the binding and internalization process. The PEGylated hemisphere of Janus particles appears dark in all images due to the gold coating. (c) A graph showing the internalization efficiency of single and clustered Janus particles in comparison to all-IgG control particles. Internalization probability was determined from live cell images of 10–18 videos from 2–6 independent samples. Scale bars: 3 μm.