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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Clin Cancer Res. 2018 Nov 29;25(5):1588–1600. doi: 10.1158/1078-0432.CCR-17-2730

Figure 1.

Figure 1.

MDM2 and p53 expression in human salivary gland mucoepidermoid carcinoma and HMC cell lines. A, Representative images of immunohistochemistry staining for MDM2 and p53 in one patient with salivary gland mucoepidermoid carcinoma and control oral mucosa. Images were taken at 200X. B, PCR analysis of total p53 RNA levels in UM-HMC-1, UM-HMC-3A, and UM-HMC-3B cells. C, Western blot analysis of p53 and MDM2 expression in UM-HMC-1, UM-HMC-3A, and UM-HMC-3B cells. D, Western blot analysis of p53 and MDM2 expression in UM-HMC-3A and UM-HMC-3B cells FACS sorted for both the ALDHhighCD44high cancer stem cell population and the remaining cells that were not ALDHhighCD44high (i.e. non-cancer stem cells).