Table 2.

Association of Baseline Tumor Characteristics and Survival by Arm

		Arm A		Arm B
	Unit for HR	HR (95%CI)	P value	HR (95%CI)	P value
Mutation burden	Log(x) mutations	0.44 (0.17 – 1.11)	0.080	1.03 (0.73 – 1.43)	0.887
PD-L1 Expression	1 %	0.65 (0.34 – 1.24)	0.194	0.96 (0.92 – 1.01)	0.125
TIL Clonality	0.1 value	0.40 (0.15 – 1.10)	0.075	0.89 (0.56 – 1.42)	0.634
T-cell fraction	Log(1%)	0.64 (0.36 – 1.13)	0.121	0.73 (0.57 – 0.95)	0.017

^*Mutation burden: Arm A (N = 30, 7 events), Arm B (n = 38, 26 events)

^**PD-L1: Arm A (N = 34, 8 events), Arm B (N = 37, 27 events)

^***TIL Clonality & T-cell fraction: Arm A (N = 39; 9 events), Arm B (N = 50, 32 events)