Table 1.
Basic demographic characteristics n (%)
| Drug-induced colitis, n = 211 | Non-inflammatory controls, n = 211 | Inflammatory controls, n = 211 | |
| Basic characteristics | |||
| Age (yr) | 62.3 ± 16.4 | 62.2 ± 16.3 | 61.8 ±15.7 |
| Gender (male) | 97 (46.0) | 97 (46.0) | 97 (46.0) |
| Height (cm) | 168.9 ± 9.5 | 168.3 ± 12.4 | 170.0 ± 9.3 |
| Body weight (kg) | 76.9 ± 22.6 | 75.0 ± 20.3 | 72.9 ± 19.7 |
| BMI (kg/m2) | 26.9 ± 7.2a1b | 26.3 ± 6.8 | 25.0 ± 5.6a3 |
| ASAb2 | |||
| ASA 1 | 0 (0) | 3 (1.4) | 0 (0) |
| ASA 2 | 133 (63.0) | 169 (80.1) | 155 (73.5) |
| ASA 3 | 70 (33.2) | 37 (17.5) | 52 (24.6) |
| ASA 4 | 8 (3.8) | 2 (0.9) | 4 (1.9) |
| ECOGb2,b3 | |||
| ECOG 0 | 0 (0) | 1 (0.5) | 2 (0.9) |
| ECOG 1 | 8 (3.8) | 75 (35.5) | 13 (6.2) |
| ECOG 2 | 149 (70.6) | 104 (49.3) | 147 (69.7) |
| ECOG 3 | 41 (19.4) | 26 (12.3) | 43 (20.4) |
| ECOG 4 | 13 (6.2) | 5 (2.4) | 6 (2.8) |
| Indication of colonoscopyb1,a2 | |||
| Diarrhoea | 73 (34.6) | 95 (45.0) | 97 (46.0) |
| Constipation | 6 (2.8) | 5 (2.4) | 1 (0.5) |
| Gastrointestinal bleeding | 63 (29.9) | 31 (14.6) | 36 (17.1) |
| Abdominal pain | 47 (22.3) | 54 (25.6) | 46 (21.8) |
| Weight loss | 6 (2.8) | 5 (2.4) | 4 (1.9) |
| Scheduled survey | 2 (0.9) | 1 (0.5) | 2 (0.9) |
| Miscellaneous | 14 (6.6) | 20 (9.5) | 25 (11.8) |
1
Drug-induced colitis vs inflammatory controls.
2
Drug-induced colitis vs non-inflammatory controls.
3
Non-inflammatory controls vs inflammatory controls.
a
P < 0.05.
b
P < 0.01. Statistical analysis was carried out with χ2 test, ANOVA or t-test as appropriate. BMI: Body mass index.