Table 2.
Comorbidities n (%)
| Comorbidity | Drug-induced colitis, n = 211 | Non-inflammatory controls, n = 211 | Inflammatory controls, n = 211 |
| Pulmonary | 39 (18.5) | 31 (14.7) | 37 (17.5) |
| Cardiac | 110 (52.1) | 93 (44.1) | 87 (41.2) |
| Neurological | 27 (12.8) | 23 (10.9) | 19 (9.0) |
| Psychiatric | 10 (4.7) | 9 (4.3) | 10 (4.7) |
| Endocrine | 47 (22.3) | 44 (20.9) | 30 (14.2) |
| Renal | 28 (13.2) | 18 (8.5) | 21 (10.0) |
| Hepatic | 11 (5.2) | 13 (6.2) | 11 (5.2) |
| Oncological | 14 (6.6) | 25 (11.8) | 17 (8.1) |
| Other | 19 (9.0) | 15 (7.1) | 16 (7.6) |
| Heart failure | 35 (16.6) | 16 (7.6)b2 | 31 (14.7)a3 |
| Renal insufficiency | 24 (11.4) | 14 (6.6) | 18 (8.5) |
| Atrial fibrillation | 26 (12.3) | 18 (8.5) | 22 (10.4) |
| Coronary heart disease | 47 (22.3) | 28 (13.3)a2 | 35 (16.6) |
| Peripheral arterial occlusive disease | 7 (3.3) | 10 (4.7) | 11 (5.2) |
| Atherosclerosis | 74 (35.1)b1 | 39 (18.5)b2 | 40 (19.0) |
| Arterial hypertension | 98 (46.4) | 97 (46.0) | 87 (41.2) |
| Diabetes mellitus | 46 (21.8) | 45 (21.3) | 32 (15.2) |
| Hypercholesterinaemia | 20 (9.5) | 16 (7.6) | 18 (8.5) |
| Hyperlipoproteinaemia | 22 (10.4)a1 | 11 (5.2)a2 | 9 (4.3) |
| Chronic obstructive lung disease | 29 (13.7) | 24 (11.4) | 27 (12.8) |
| Stroke | 14 (6.6) | 9 (4.3) | 11 (5.2) |
| Smoking | 77 (36.7) | 66 (31.3) | 78 (37.0) |
| Surgery | 9 (4.3) | 1 (0.5)a2 | 3 (1.4) |
| Intensive care therapy | 9 (4.3) | 2 (0.9)a2 | 4 (3.1) |
1
Drug-induced colitis vs inflammatory controls.
2
Drug-induced colitis vs non-inflammatory controls.
3
Non-inflammatory controls vs inflammatory controls.
a
P < 0.05.
b
P < 0.01.
Statistical analysis was carried out with χ2 test.