Table 3.
Characteristics |
Univariable |
Multivariable |
||||
IRR | 95%CI | P value | aIRR | 95%CI | P value | |
Female gender | 1.68 | 1.08-2.60 | 0.02 | 1.92 | 1.23-2.99 | 0.004 |
Non-Hispanic Caucasian | 0.86 | 0.55-1.35 | 0.52 | |||
Age per year | 1.00 | 0.98-1.03 | 0.80 | |||
Hypertension | 1.31 | 0.84-2.04 | 0.24 | |||
Diabetes mellitus | 1.05 | 0.65-1.69 | 0.85 | |||
Coronary artery disease | 0.52 | 0.18-1.55 | 0.28 | |||
Stroke | 0.20 | 0.03 0 1.16 | 0.13 | |||
Dialysis | 1.63 | 0.55-4.87 | 0.34 | |||
BMI per 1 kg/m2 | 1.01 | 0.98-1.05 | 0.42 | |||
Autoimmune1 | 0.59 | 0.32-1.09 | 0.11 | |||
MELDNa per 1 point | 1.09 | 1.04-1.14 | < 0.001 | 1.08 | 1.03-1.13 | 0.001 |
Albumin per 1 mg/dL | 0.58 | 0.39-0.84 | 0.005 | 0.47 | 0.31-0.70 | < 0.001 |
Ascites | 1.72 | 1.09-2.70 | 0.02 | |||
NCT per 1 s | 1.00 | 1.00-1.01 | 0.13 | |||
Moderate/severe HE | 1.28 | 0.82-1.98 | 0.28 | |||
Frail | 2.12 | 1.17-3.81 | 0.007 |
Combined autoimmune hepatitis, primary sclerosing cholangitis, and primary biliary cholangitis. IRR: Incidence rate ratio; CI: Confidence interval; aIRR: Adjusted incidence rate ratio; BMI: Body mass index; MELDNa: Model for end-stage liver disease with serum sodium; NCT: Numbers connection test; HE: Hepatic encephalopathy.