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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Clin Biochem. 2019 Jan 15;65:45–52. doi: 10.1016/j.clinbiochem.2019.01.002

Table 2:

Prognostic ability of individual and combined miRs (Log2FC) to differentiate TACE responders from non-responders in serum samples collected from HCC patients

Groups Predictor miR(s) Cut-off value Sensitivity Specificity AUC SEM p-value
% %
CR vs NR miR-26a 0.807 100.00 100.00 1.000 0.000 <0.001
miR-107 1.160 86.70 70.60 0.741 0.092 0.020
miR-133 0.037 100.00 94.40 0.997 0.006 <0.001
miR-26a & miR-133 1.000 0.000 <0.001
CR vs PR miR-133 0.940 93.80 88.20 0.919 0.059 <0.001
miR-26a & miR-133 0.934 0.057 <0.001
*(CR+PR) vs NR miR-133 −1.600 97.00 83.30 0.965 0.028 <0.001
miR-26a & miR-133 0.998 0.003 <0.001
PR vs NR miR-26a 1.490 94.10 83.30 0.958 0.030 <0.001
miR-106b 0.328 76.50 66.70 0.761 0.081 <0.001
miR-133 −1.530 94.10 83.30 0.935 0.050 <0.001
miR-26a & miR-133 0.997 0.005 <0.001

AUC=Area under ROC curve, CR=complete responders, PR=Partial responders, NR=non-responders to TACE.

*

Responders=CR+PR pooled together and compared to NR