Table 2:
Groups | Predictor miR(s) | Cut-off value | Sensitivity | Specificity | AUC | SEM | p-value |
---|---|---|---|---|---|---|---|
% | % | ||||||
CR vs NR | miR-26a | 0.807 | 100.00 | 100.00 | 1.000 | 0.000 | <0.001 |
miR-107 | 1.160 | 86.70 | 70.60 | 0.741 | 0.092 | 0.020 | |
miR-133 | 0.037 | 100.00 | 94.40 | 0.997 | 0.006 | <0.001 | |
miR-26a & miR-133 | 1.000 | 0.000 | <0.001 | ||||
CR vs PR | miR-133 | 0.940 | 93.80 | 88.20 | 0.919 | 0.059 | <0.001 |
miR-26a & miR-133 | 0.934 | 0.057 | <0.001 | ||||
*(CR+PR) vs NR | miR-133 | −1.600 | 97.00 | 83.30 | 0.965 | 0.028 | <0.001 |
miR-26a & miR-133 | 0.998 | 0.003 | <0.001 | ||||
PR vs NR | miR-26a | 1.490 | 94.10 | 83.30 | 0.958 | 0.030 | <0.001 |
miR-106b | 0.328 | 76.50 | 66.70 | 0.761 | 0.081 | <0.001 | |
miR-133 | −1.530 | 94.10 | 83.30 | 0.935 | 0.050 | <0.001 | |
miR-26a & miR-133 | 0.997 | 0.005 | <0.001 |
AUC=Area under ROC curve, CR=complete responders, PR=Partial responders, NR=non-responders to TACE.
Responders=CR+PR pooled together and compared to NR