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. 2019 Feb 25;10:129. doi: 10.3389/fpsyg.2019.00129

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Copyright © 2019 Santarnecchi, Bossini, Vatti, Fagiolini, La Porta, Di Lorenzo, Siracusano, Rossi and Rossi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Common substrate for psychological benefit. Changes in CAPS total score are accompanied by two patterns of FC changes after both EMDR and TF-CBT (A). Increased connectivity between superior frontal gyrus and right temporal pole regions, and decreased connectivity between left visual cortex and left temporal pole, explain positive changes in CAPS after psychotherapy. Results are shown for the pairwise atlas-based analysis (p < 0.05, FDR corrected) (A) and confirmed with seed-based connectivity analysis (p < 0.05, cluster-based correction) (B). The FC profile of the seed region located in the superior frontal gyrus is also displayed (^∗), highlighting its resemblance with the supplementary motor cortex. SFG, superior frontal gyrus; MTG, middle temporal gyrus; FDR, False Discovery Rate.