Table 3.
Comparisons of COG functional abundance between healthy (H) and diarrhea (D) groups.
| Function code | Description | Median abundance |
p-value | |
|---|---|---|---|---|
| H | D | |||
| G | Carbohydrate transport and metabolism | 2037230 | 1512602 | 0.00951∗∗ |
| S | Function unknown | 1789903 | 1510502 | 0.0678 |
| E | Amino acid transport and metabolism | 1727646 | 1377096 | 0.0365∗ |
| R | General function prediction only | 1725785 | 1386180 | 0.0507 |
| K | Transcription | 1646558 | 1212702 | 0.0502 |
| M | Cell wall/membrane/envelope biogenesis | 1486729 | 1166449 | 0.0734 |
| L | Replication, recombination and repair | 1449998 | 1308059 | 0.1677 |
| J | Translation, ribosomal structure and biogenesis | 1411434 | 1251860 | 0.0723 |
| P | Inorganic ion transport and metabolism | 1315868 | 990624.3 | 0.0513 |
| C | Energy production and conversion | 1283908 | 959898.9 | 0.0492∗ |
| T | Signal transduction mechanisms | 1125981 | 722264.6 | 0.0501 |
| H | Coenzyme transport and metabolism | 745593.3 | 600065.6 | 0.00529∗∗ |
| F | Nucleotide transport and metabolism | 691720.9 | 595203.4 | 0.00883∗∗ |
| O | Posttranslational modification, protein turnover, chaperones | 688619.6 | 566269.2 | 0.00682∗∗ |
| V | Defense mechanisms | 602100.1 | 471338.2 | 0.00349∗∗ |
| I | Lipid transport and metabolism | 523449.2 | 416518.3 | 0.00721∗∗ |
| U | Intracellular trafficking, secretion, and vesicular transport | 336953 | 283189.2 | 0.0629 |
| D | Cell cycle control, cell division, chromosome partitioning | 301444.1 | 24585.71 | 0.0506 |
| N | Cell motility | 194057.2 | 142038.9 | 0.0612 |
| Q | Secondary metabolites biosynthesis, transport and catabolism | 187739.7 | 137872.2 | 0.0785 |
| B | Chromatin structure and dynamics | 2972 | 1926.056 | 0.0663 |
| Z | Cytoskeleton | 1934.6 | 1056 | 0.0623 |
| A | RNA processing and modification | 998.35 | 1241.056 | 0.0734 |
| W | Extracellular structures | 149.3 | 348.9 | 0.00236∗∗ |
| Y | Nuclear structure | 2.5 | 0.11 | 0.00591∗∗ |
∗p < 0.05 and ∗∗p < 0.01.