FIGURE 3.

Two possible ways in which TBLs may establish the acetylation pattern. A highly simplified hypothesis of how acetylation patterns may be established by TBL proteins, this model does not incorporate interactions with glucuronic acids or post-synthesis modification by acetyl esterases. (A) Acetylation pattern may occur in a hierarchical or sequential manner where TBL genes are expressed in a certain order for the final pattern to be obtained or the enzyme kinetics determines the order in which the TBL proteins modify the backbone. (B) Certain patterns of acetylation occur when a combination of TBL proteins are present, these TBLs either interact with each other or share transcriptional regulation. The acetylation patterns shown here are hypothetical in order to illustrate the concept. Each TBL of a different color refers to a different TBL.