Table 1.
Baseline clinical characteristics of EVA patients according to pre-admission medication adherence.
| Low adherence (n = 67) | Medium-high adherence (n = 213) | p | |
|---|---|---|---|
| Age, years median [IQR] | 68 [61–78] | 71 [63–76] | 0.447 |
| Women, n (%) | 24 (35.8) | 74 (34.7) | 0.872 |
| BMI, kg/m2 median [IQR] | 27.0 [24.8–30.0] | 26.5 [24.2–29.5] | 0.447 |
| SBP, mmHg median [IQR] | 130 [120–150] | 130 [120–140] | 0.104 |
| DBP, mmHg median [IQR] | 80 [70–85] | 80 [70–80] | 0.537 |
| HR, bpm median [IQR] | 70 [62–80] | 70 [60–76] | 0.239 |
| Hypertension | 57 (86.4) | 181 (85.0) | 0.781 |
| Dyslipidemia | 41 (61.2) | 122 (57.3) | 0.571 |
| Type 2 diabetes | 27 (40.3) | 58 (27.2) | 0.042 |
| Active Smoke | 15 (22.7) | 49 (23.2) | 0.934 |
| Alcohol Abuse | 11 (16.4) | 36 (17.7) | 0.805 |
| Physical inactivity | 57 (85.1) | 167 (78.4) | 0.234 |
| History of CAD | 28 (41.8) | 79 (37.1) | 0.490 |
| Vascular disease | 21 (31.8) | 58 (27.2) | 0.470 |
| Stroke/TIA | 7 (10.6) | 24 (11.3) | 0.881 |
| CKD | 17 (26.2) | 53 (25.7) | 0.945 |
| Polypharmacy | 38 (56.7) | 106 (49.8) | 0.321 |
| DASI, median [IQR] | 27.0 [19.0–42.7] | 32.2 [19.0–49.8] | 0.153 |
| Therapy pre-admission | |||
| - Glucose lowering drugs | 17 (25.4) | 41 (19.2) | 0.281 |
| - Insulin | 7 (10.4) | 12 (5.6) | 0.172 |
| - Statins | 32 (47.8) | 110 (51.6) | 0.579 |
| - Antiplatelets | 43 (64.2) | 135 (63.4) | 0.906 |
| - Anticoagulants | 8 (11.9) | 19 (8.9) | 0.465 |
| - Beta-Blockers | 30 (44.8) | 96 (45.1) | 0.966 |
| - ACEi | 19 (28.4) | 57 (26.8) | 0.798 |
| - ARBs | 18 (26.9) | 76 (35.7) | 0.183 |
Data are presented as number of patients (%) unless otherwise specified.
IQR, interquartile range; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; HR, heart rate; CAD, coronary artery disease; TIA, Transient ischemic attack; CKD, chronic kidney disease; DASI, Duke Activity Status Index; ACEi, Angiotensin converting enzyme inhibitors; ARBs, Angiotensin II receptor blockers. When missing data are more than 10%, they are reported in brackets.