Table 2.

Univariate and multivariate analyses identified factors affecting OS of patients with NSCLC

	Univariate analysis			Multivariate analysis
Clinical parameters	HR	95% CI	P	HR	95% CI	P
TNFR2	2.371	1.135–4.953	0.022*	2.332	1.057–5.144	0.036*
Gender	1.050	0.530–2.079	0.890	0.521	0.236–1.153	0.108
Age (year)	0.908	0.455–1.816	0.787	1.203	0.541–2.677	0.650
Tumor size	2.195	0.907–5.312	0.081	1.425	0.466–4.360	0.535
Clinical stage	0.078	0.036–0.167	0.000*	0.039	0.014–0.106	0.000*
Regional lymph node involvement	0.229	0.113–0.465	0.000*	1.142	0.382–3.413	0.000*
Histological type degree
Adenocarcinoma	0.643	0.189–2.187	0.480	0.244	0.064–0.929	0.039*
Squamous	0.684	0.195–2.405	0.554	0.906	0.243–3.375	0.883

^* P < 0.05 was considered statistically significant.

CI, confidence interval; HR, hazard ratio; NSCLC, non‐small cell lung cancer; OS, overall survival.