Table 1.
Characteristics of study population.
| SLE patients (70) | Healthy subjects (50) | P value∗ | |
|---|---|---|---|
| Gender (female/male) | 64/6 | 35/15 | 0.0032 |
| Age (years, median (IQR)) | 46.5 (38.0-57.8) | 44 (34.8-50.0) | 0.1174 |
| Serology | |||
| EBV-seropositive | 68 | 46 | |
| EBV-seronegative | 2 | 4 | 0.2331 |
| HCMV-seropositive | 56 | 35 | |
| HCMV-seronegative | 14 | 15 | 0.2795 |
| DNAemia | |||
| EBV DNA-positive | 30 | 4 | <0.0001 |
| HCMV DNA-positive | 3 | 0 | 0.2821 |
| Viral load | |||
| EBV DNA (copies/ml, median (IQR)) | 233 (100-656.3) | 125 (62.5-225) | 0.1895 |
| HCMV DNA (copies/ml, median (IQR)) | 200 (100-1000) | Undetectable | |
| Immunosuppression | |||
| lp-IS | 25 | ||
| mhp-IS | 45 | ||
| SLEDAI score | |||
| <4 | 45 | ||
| ≥4 | 25 | ||
Demographic characteristics of SLE population and healthy controls are summarized in the table. (∗) P values were calculated using Fisher's exact test.