Figure 1.
Low S100A8 expression and high oxidative stress in lung tissue from patients with emphysema. (A and B) Western blot images of expression and quantification of S100A8 protein (A) and S100A8 mRNA levels (B) in lung tissue obtained from nonsmokers (NS), smokers (SM), and patients with emphysema (E). Quantification of S100A8 expression was normalized to β-actin and control nonsmokers. (C) Western blot images of expression and quantification of 4-hydroxynonenal (4-HNE) in lung tissue from NS, SM, and patients with E. (D) Correlation analysis of 4-HNE and S100A8 protein expression. *P < 0.05; **P < 0.001. Data are shown as means ± SD.