Comparison 1. 0 ppm F versus 1000 ppm F in adults (mature permanent dentition).

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 DMFS	3	2162	Mean Difference (IV, Random, 95% CI)	‐0.53 [‐1.02, ‐0.04]
2 DMFT	1		Mean Difference (IV, Random, 95% CI)	Subtotals only